Acetylcholine Receptor Binding Antibody (AChR) Test

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About Our Acetylcholine Receptor Binding Antibody (AChR) Test

The Acetylcholine Receptor (AChR) Binding Antibody test is a specialized blood test used to help diagnose Myasthenia Gravis (MG), a chronic autoimmune neuromuscular disorder that causes muscle weakness and fatigue. This condition occurs when the immune system mistakenly produces antibodies that interfere with normal nerve-to-muscle communication.

In healthy muscle function, acetylcholine acts as a chemical messenger that allows nerves to signal muscles to contract. In Myasthenia Gravis, AChR antibodies disrupt this process, leading to weakened muscle responses that often worsen with activity and improve with rest.

This test specifically measures AChR binding antibodies, the most common and clinically significant antibodies associated with MG. These antibodies are present in approximately 85–90% of individuals diagnosed with Myasthenia Gravis, making this test the primary and most reliable screening tool for the condition.

Because AChR antibodies are not normally found in the blood, their presence strongly suggests an autoimmune cause of muscle weakness. Identifying these antibodies early helps support accurate diagnosis, guide further testing, and enable timely treatment to improve muscle strength and quality of life.

What Is Included In This Test?

This test measures the presence and level of acetylcholine receptor binding antibodies in the blood.

Your results can help:

Support the diagnosis of Myasthenia Gravis
Distinguish MG from other causes of muscle weakness or fatigue
Confirm autoimmune disruption of nerve-to-muscle signaling
Guide follow-up testing for modulating or blocking antibodies if needed
Assist in treatment planning and disease monitoring

A positive binding antibody result is highly specific for Myasthenia Gravis and is rarely present in individuals without the condition.

Who Should Consider This Test?

This test is ideal for individuals experiencing symptoms suggestive of neuromuscular dysfunction.

You should consider this test if you:

Have persistent muscle weakness that worsens with activity
Experience drooping eyelids, double vision, or facial muscle fatigue
Have difficulty chewing, swallowing, or speaking
Have unexplained muscle fatigue that improves with rest
Are being evaluated for suspected Myasthenia Gravis

Early diagnosis allows for more effective treatment and improved long-term symptom management.

Convenient, No-Appointment Testing

To complete your test:

Order online through our website
Use the lab locator to find a nearby testing location
Walk in; no appointment required
Access your results securely in your HealthLabs.com account within one to three business days

110% Price Guarantee!

If you find the same test for a lower price from a comparable provider, contact us. We not only match the price, we beat it by an additional 10 percent of the difference.

Common Questions:

What condition does this test diagnose?

The test is primarily used to diagnose Myasthenia Gravis, an autoimmune neuromuscular disorder.

Are AChR antibodies found in healthy individuals?

No, these antibodies are not normally present in healthy people.

Will anyone see my results besides me?

Your results are stored in your secure online account. They are not shared with anyone else. If you choose, you can print or download them to share with your own doctor.

Do I need to fast before this test?

Fasting is not required for this panel. You can eat and drink normally unless your doctor has given you other instructions.

Can I talk to someone about my results?

Yes. If your results come back abnormal or if you simply have questions, our team is here to support you. You can text our Patient Services team at 1800-579-3914.

Can I use insurance to pay for this test?

In order to ensure your privacy, we do not bill insurance directly, but you may use HSA or FSA funds. This keeps your results and testing completely private from insurers. We can also provide you with an itemized receipt for insurance reimbursement purposes if you need it.