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ANA Blood Test (Antinuclear Antibodies)

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About Our ANA Blood Test (Antinuclear Antibodies)

The Antinuclear Antibodies (ANA) test measures antibodies in your blood that mistakenly target your own cells, a process known as an autoimmune reaction. These antibodies are commonly associated with autoimmune and connective tissue disorders, making this test a key first step in evaluating unexplained inflammation, fatigue, joint pain, or systemic symptoms.

ANA testing is widely used to help identify immune system dysfunction and support the diagnosis of autoimmune conditions. Because ANA patterns can provide important clinical clues, results are interpreted alongside symptoms and additional lab findings to guide accurate diagnosis and next steps.


What Is Included In This Test?

This test detects the presence and pattern of antinuclear antibodies in your blood using validated laboratory methods.

Your results can help:

  • Screen for autoimmune and connective tissue diseases
  • Support diagnosis of conditions such as lupus, Sjögren’s syndrome, and scleroderma
  • Evaluate immune system activity related to chronic inflammation
  • Assist in diagnosing drug-induced autoimmune conditions
  • Guide further autoimmune-specific testing when needed

Who Should Consider This Test?

This test is ideal for individuals experiencing symptoms that may indicate an autoimmune or inflammatory condition.

You should consider this test if you:

  • Have persistent joint or muscle pain
  • Experience unexplained fatigue, rashes, or fevers
  • Have symptoms suggestive of lupus, Sjögren’s syndrome, or other connective tissue disorders
  • Are being evaluated for autoimmune hepatitis or drug-induced lupus
  • Have Raynaud’s symptoms or other systemic inflammatory signs

Early identification of autoimmune activity can help guide timely treatment and improve long-term outcomes.


Convenient, No-Appointment Testing

To complete your test:

  1. Order online through our website
  2. Use the lab locator to find a nearby testing location
  3. Walk in; no appointment required
  4. Access your results securely in your HealthLabs.com account within one to three business days

110% Price Guarantee!

If you find the same test for a lower price from a comparable provider, contact us. We not only match the price, we beat it by an additional 10 percent of the difference.


Common Questions:

Is the ANA test used to diagnose lupus?

Yes, ANA testing is a key screening tool for lupus, as most people with lupus have a positive ANA result.

What are antinuclear antibodies?

Antinuclear antibodies are immune proteins that mistakenly target the nucleus of healthy cells, which can occur in autoimmune conditions.

Will anyone see my results besides me?

Your results are stored in your secure online account. They are not shared with anyone else. If you choose, you can print or download them to share with your own doctor.

Do I need to fast before this test?

Fasting is not required for this panel. You can eat and drink normally unless your doctor has given you other instructions.

Can I talk to someone about my results?

Yes. If your results come back abnormal or if you simply have questions, our team is here to support you. You can text our Patient Services team at 1800-579-3914, anytime between 8am and 8pm.

Can I use insurance to pay for this test?

In order to ensure your privacy, we do not bill insurance directly, but you may use HSA or FSA funds. This keeps your results and testing completely private from insurers. We can also provide you with an itemized receipt for insurance reimbursement purposes if you need it.

What type of sample is required for this test?

This test requires a simple blood draw. No urine samples, swabs, or physical exams are involved.


Medically Reviewed by: 2026-01-21


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