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Cancer Antigen 125 Test

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About Our Cancer Antigen 125 Test

The Cancer Antigen 125 (CA-125) test is a blood test that measures the level of CA-125, a protein often found on the surface of ovarian cancer cells. Because elevated CA-125 levels are commonly associated with ovarian cancer, this test is widely used as a tumor marker to support diagnosis and ongoing disease management.

CA-125 testing plays an important role after an ovarian cancer diagnosis by helping monitor how well treatment is working. Changes in CA-125 levels over time can indicate whether cancer is responding to therapy or if additional evaluation may be needed.

This test is also valuable for follow-up care. Rising CA-125 levels after treatment may suggest cancer recurrence, often before symptoms appear, allowing for earlier clinical intervention. While CA-125 can be elevated in other cancers or certain non-cancerous conditions, trends over time are especially meaningful when interpreted by a healthcare provider.

Ovarian cancer risk increases with age and family history. It is most commonly diagnosed after menopause, with higher incidence in women over 60. Genetic factors also play a role, and risk can be inherited from either the maternal or paternal side. The CA-125 test supports proactive monitoring for individuals at increased risk or undergoing ovarian cancer care.


What Is Included In This Test?

This test measures the level of Cancer Antigen 125 (CA-125) in the blood.

Your results can help:

  • Support diagnosis of ovarian cancer
  • Monitor response to ovarian cancer treatment
  • Detect potential cancer recurrence
  • Track disease progression over time
  • Guide follow-up testing or imaging when needed

CA-125 levels are most meaningful when evaluated as a trend rather than a single result.


Who Should Consider This Test?

This test is ideal for individuals who need monitoring or evaluation related to ovarian cancer.

You should consider this test if you:

  • Have been diagnosed with ovarian cancer
  • Are currently undergoing ovarian cancer treatment
  • Need post-treatment monitoring for recurrence
  • Have a strong family history of ovarian cancer
  • Are at increased genetic risk and under medical surveillance

This test is not typically used as a general screening tool but is highly valuable for monitoring and follow-up care.


Convenient, No-Appointment Testing

To complete your test:

  1. Order online through our website
  2. Use the lab locator to find a nearby testing location
  3. Walk in; no appointment required
  4. Access your results securely in your HealthLabs.com account within one to three business days

110% Price Guarantee!

If you find the same test for a lower price from a comparable provider, contact us. We not only match the price, we beat it by an additional 10 percent of the difference.


Common Questions:

What does the CA-125 test measure?

It measures the level of Cancer Antigen 125, a protein often elevated in ovarian cancer.

How is CA-125 used after an ovarian cancer diagnosis?

It helps monitor treatment response and detect possible recurrence.

Will anyone see my results besides me?

Your results are stored in your secure online account. They are not shared with anyone else. If you choose, you can print or download them to share with your own doctor.

Do I need to fast before this test?

Fasting is not required for this panel. You can eat and drink normally unless your doctor has given you other instructions.

Can I talk to someone about my results?

Yes. If your results come back abnormal or if you simply have questions, our team is here to support you. You can text our Patient Services team at 1800-579-3914.

Can I use insurance to pay for this test?

In order to ensure your privacy, we do not bill insurance directly, but you may use HSA or FSA funds. This keeps your results and testing completely private from insurers. We can also provide you with an itemized receipt for insurance reimbursement purposes if you need it.

What type of sample is required for this test?

This test requires a simple blood draw. No urine samples, swabs, or physical exams are involved.


Medically Reviewed by: 2026-01-23


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