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Celiac Disease Antibody Screening Test

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About Our Celiac Disease Antibody Screening Test

Note: Fasting is not required for this test.

This blood test is used to determine the presence of certain antibodies associated with celiac disease. Celiac disease is a gluten intestinal disease occurring in both children and adults. The condition is characterized by a sensitivity to gluten (found in wheat, barley, and rye) that causes inflammation and atrophy of the villi of the small intestine, malabsorption, etc.

Our Celiac Disease Antibody Screening Test screens for the presence of Tissue Transglutaminase antibody (IgG, IgA) and Gliadin antibody (IgG, IgA) in the blood. Celiac disease is characterized by the presence of Transglutaminase, Gliadin, and Reticulin antibodies. Such patients display a hypersensitivity to gluten (found in wheat, rye and barley) in their diet. The antibody is undetectable when patients with hypersensitivity are placed on gluten-free diets. Antibody IgA is more specific and IgG is more sensitive to Celiac disease.

This sensitivity to gluten may also be seen in dermatitis herpetiformis. Strict avoidance of gluten in the diet will control the disease's activity, and antibodies to serum markers will disappear with time.


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