Estrone Test

This test measures the amount of Estrone in the blood. 

Estrone is a female sex hormone that forms in the glands and fatty tissue, as well as in the ovaries. It is considered the weakest of the 3 types of estrogen. Estrogen is also 1 of the 2 main sex hormones in females, the other being progesterone. 

The three types of estrogen are:

• Estrone (E1) 
• Estradiol (E2)
• Estriol (E3)

Estrone is also the only form of estrogen that a body continues to naturally produce after menopause. Postmenopausal people typically have higher estrone levels than premenopausal individuals. Males, and people designated male at birth also have estrone, however, their levels are much lower than people designated female at birth.

Estrone in Women & Men

In women, Estrone plays a key role in:

• Female Sexual Function
• Reproduction Health
• Estrogen Conversion
• Releasing mature eggs during the menstrual cycle
• Thickening the uterine lining to prepare for fertilization

In both genders, Estrone plays a key role in:

• Bone Health.
• Cognitive Function.
• Production of nitric oxide (molecules that assists blood vessels to open).

Estrone Levels in Women & Men

Low Estrone

In people designated female at birth, low estrone levels can lead to:

• Abnormal uterine bleeding (AUB).
• Difficulty sleeping.
• Dry skin.
• Irregular periods.
• Menstrual migraines (Headaches right before period starts).

In people designated male at birth, low estrone may lead to:

• Increased belly fat.
• Lower sex drive.

High Estrone

In people designated female at birth, high estrone levels may cause:

• Depression and/or anxiety.
• Fatigue.
• Heavy and/or light periods.
• Low sex drive.
• Lumps in breast tissue.
• Severe premenstrual syndrome (PMS).
• Uterine fibroids.
• Weight gain.

For people designated male at birth, high estrone levels may cause:

• Enlarged breast tissue.
• Erectile dysfunction.
• Infertility.