CD4 cells help coordinate immune response and are a key marker of immune health, especially in HIV.
Lymphocyte Subset Panel
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About Our Lymphocyte Subset Panel
The Lymphocyte Subset Test Panel is a comprehensive blood test designed to evaluate the strength and balance of your immune system. It measures specific types of white blood cells called lymphocytes, which play a critical role in protecting your body from infections, viruses, and abnormal cell growth. By analyzing these immune cells in detail, this test provides a clear picture of your immune health.
Your immune system is made up of specialized cells including T cells, B cells, and natural killer cells. Each type serves a unique function. T cells coordinate immune response and attack infected cells, B cells produce antibodies to fight bacteria and viruses, and natural killer cells help defend against viral infections and tumor cells. When the balance of these cells shifts, it can signal immune dysfunction or disease.
This test is especially important in monitoring conditions that affect immune function, including HIV infection. In individuals living with HIV, CD4 cell counts and the CD4 to CD8 ratio are key indicators of immune strength and treatment effectiveness. Changes in these values help guide clinical decisions and therapy management.
Beyond HIV monitoring, lymphocyte subset analysis helps detect primary immunodeficiencies, evaluate recurrent infections, and classify complex immune disorders such as severe combined immunodeficiency. Whether assessing immune weakness, monitoring treatment response, or investigating unexplained infections, this panel delivers critical insight into immune system performance.
What Is Included In This Test?
This panel measures detailed immune cell counts and proportions, including:
- Absolute lymphocyte count
- Absolute CD3 and percentage CD3, total T cells
- Absolute CD4 and percentage CD4, helper T cells
- Absolute CD8 and percentage CD8, cytotoxic T cells
- CD4 to CD8 ratio, calculated
- Absolute CD16 and CD56 and percentage CD16 and CD56, natural killer cells
- Absolute CD19 and percentage CD19, B cells
Why Does This Test Matter?
Your immune system depends on proper balance between T cells, B cells, and natural killer cells. When these levels fall outside normal ranges, it may increase the risk of infection, indicate disease progression, or reveal underlying immune dysfunction.
For individuals with HIV, CD4 cell count is one of the most important indicators of immune status. Monitoring these levels helps determine disease stage, assess treatment response, and guide decisions about therapy adjustments.
This test is also essential for diagnosing and classifying primary immunodeficiency disorders. Identifying isolated T cell, B cell, or natural killer cell deficiencies helps physicians predict infection risk and tailor management strategies.
By providing detailed immune profiling, this panel supports proactive care, early detection of immune compromise, and informed treatment planning.
Who Should Consider This Test?
This test is recommended for individuals who need immune system evaluation or monitoring.
You should consider this test if you:
- Are living with HIV and require routine monitoring
- Have recurrent or unusual infections
- Are being evaluated for immune deficiency
- Have unexplained immune-related symptoms
- Are undergoing immune-suppressing therapy
- Need classification of a suspected primary immunodeficiency
Convenient, No-Appointment Testing
To complete your test:
- Order online through our website
- Use the lab locator to find a nearby testing location
- Walk in; no appointment required
- Access your results securely in your HealthLabs.com account within one to three business days
110% Price Guarantee!
If you find the same test for a lower price from a comparable provider, contact us. We not only match the price, we beat it by an additional 10 percent of the difference.
Common Questions:
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Why is CD4 important?
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Can this test diagnose HIV?
No it monitors immune status in individuals with HIV but does not diagnose infection.
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Will anyone see my results besides me?
Your results are stored in your secure online account. They are not shared with anyone else. If you choose, you can print or download them to share with your own doctor.
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Do I need to fast before this test?
Fasting is not required for this panel. You can eat and drink normally unless your doctor has given you other instructions.
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Can I talk to someone about my results?
Yes. If your results come back abnormal or if you simply have questions, our team is here to support you. You can text our Patient Services team at 1800-579-3914.
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Can I use insurance to pay for this test?
In order to ensure your privacy, we do not bill insurance directly, but you may use HSA or FSA funds. This keeps your results and testing completely private from insurers. We can also provide you with an itemized receipt for insurance reimbursement purposes if you need it.
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What type of sample is required for this test?
This test requires a simple blood draw. No urine samples, swabs, or physical exams are involved.