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About Our Liver Function Test
Note: Fasting is not required for this test.
The Liver Function Test (or Hepatic Function Test) is a blood test panel that includes several tests that measure specific proteins and liver enzymes to get an overall sense of how well the liver working.
The liver filters the blood coming from the digestive tract, before passing it along to the rest of the body. This organ also detoxifies chemicals and metabolizes drugs and secretes bile that ends up back in the intestines. The liver also makes proteins that are important for blood clotting and other functions.
The Liver Function Test Panel's combination of blood tests helps determine overall liver health:
- Alanine aminotransferase (ALT/SGPT) - ALT is an enzyme found predominantly in the cells of the liver. When the liver is damaged, ALT is released into the blood.
- Albumin - Albumin is a protein made by the liver. Measuring levels of albumin is helpful in diagnosing liver disease. An albumin test measures how well your liver is making the proteins that your body needs.
- Albumin/Globulin Ratio (calculated) - The A/G ratio is calculated from measured total protein, measured albumin, and calculated globulin (total protein - albumin) to help diagnose diseases.
- Alkaline phosphatase (ALP) - In conditions affecting the liver, damaged liver cells release increased amounts of ALP into the blood.
- Aspartate aminotransferase (AST/SGOT) - AST is a liver enzyme that is useful in helping to diagnose liver diseases.
- Bilirubin, Direct - Bilirubin is made in the body when old red blood cells are broken down. Bilirubin attached to sugar is called “direct” or “conjugated” bilirubin.
- Bilirubin, Indirect - Bilirubin that is not attached to sugar is called “indirect” or “unconjugated” bilirubin.
- Bilirubin, Total - This test measure direct and indirect levels of bilirubin for a total bilirubin value. In cases of excess bilirubin, an obstruction, or an inflamed liver, the liver cannot process the bilirubin in the body because. When the body has too much bilirubin, your skin and the whites of your eyes will start to yellow causing a condition called jaundice.
- Globulin (calculated) - Globulin is a protein made in your liver and helps the immune system fight infections. Low globulin levels can be a sign of liver damage or other conditions.
- Total Protein - Total protein measurements can help diagnose liver diseases. Total Protein measures the amount of protein in your blood. The two main proteins found in the blood are globulins and albumin.