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HIV 4th Generation Duo Antigen/Antibody Test Popular

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About Our HIV 4th Generation Duo Antigen/Antibody Test

The HIV 4th Generation Test is an advanced, highly accurate screening method that detects HIV earlier than traditional tests by identifying both HIV antibodies and the p24 antigen, one of the earliest markers of infection. Because it captures infections during the earliest and most infectious stage, the 4th generation test is the preferred choice for timely diagnosis, informed decision-making, and protecting your long-term health.


Why Choose the 4th Generation HIV Test?

This advanced blood test identifies both HIV antibodies and the p24 antigen, allowing it to detect HIV 4–12 days earlier than older 3rd-generation tests. That means you get answers sooner — and peace of mind faster.


How the Test Works, and Why It’s More Accurate:

Unlike older tests that only look for the body’s antibody response, this test detects two key markers:

1. HIV Antibodies: These are proteins your immune system creates in response to the virus. Antibodies take time to develop, which is why older tests required longer waiting periods.

2. HIV p24 Antigen: This is a viral protein produced in high amounts shortly after infection — often before antibodies are detectable. The presence of p24 allows this test to catch infections during the earliest and most infectious stage.

By combining these markers, the 4th generation test offers the broadest detection window and the strongest early-detection capability available in routine HIV screening.


Know the Symptoms (But Don’t Wait for Them):

HIV can begin with mild, flu-like symptoms, or sometimes no symptoms at all. If you’ve had a potential exposure, testing is the only way to know.

Early (Acute) HIV Symptoms May Include:

  • Fever, sore throat, headache
  • Chills or night sweats
  • Swollen lymph nodes
  • Joint or muscle pain
  • Rash
  • Diarrhea
  • Mouth or genital ulcers

Chronic HIV Symptoms May Include:

  • Ongoing fever
  • Fatigue
  • Diarrhea
  • Weight loss
  • Coughing or shortness of breath
  • Swollen lymph nodes

Without treatment, HIV can progress over years to AIDS, which includes more severe symptoms such as persistent fever, chronic diarrhea, rapid weight loss, and mouth lesions.


Who Should Consider This Test?

You may benefit from the 4th Generation HIV Test if:

  • You have had multiple or new sexual partners
  • You are entering a new relationship and both partners want a comprehensive check
  • You have had unprotected sex and want broad testing in one visit
  • You want STD screenings without scheduling a doctor’s visit first

110% Price Guarantee!

If you find the same test for a lower price from a comparable provider, contact us. We not only match the price, we beat it by an additional 10 percent of the difference.



Common Questions:

Will the HIV 4th Generation Test detect HIV even if I don’t have symptoms?

Yes. Many people with early HIV have no symptoms at all, and symptoms alone are not reliable. The 4th generation test detects markers of HIV infection regardless of whether you feel sick.

Do I need to fast before this test?

Fasting is not required for this test. You can eat and drink normally unless your doctor has given you other instructions.

Will anyone see my results besides me?

Your results are stored in your secure online account. They are not shared with anyone else. If you choose, you can print or download them to share with your own doctor.

Can I talk to someone about my results?

Yes. If your results come back positive or if you simply have questions, our team is here to support you. You can text our Patient Services team at 1800-579-3914, anytime between 8am and 8pm.

Can I use insurance to pay for this test?

In order to ensure your privacy, we do not bill insurance directly, but you may use HSA or FSA funds. This keeps your results and testing completely private from insurers. We can also provide you with an itemized receipt for insurance reimbursement purposes if you need it.

What type of sample is required for this test?

This test requires a simple blood draw. No urine samples, swabs, or physical exams are involved.


Medically Reviewed by: 2019-03-06

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