Immunity means your body has developed protection against a specific virus. For hepatitis A and B, this can occur from past infection or vaccination. There is currently no vaccine for hepatitis C.
Hepatitis A, B, & C Antibodies Confirmation Panel
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About Our Hepatitis A, B, & C Antibodies Confirmation Panel
Hepatitis A, B, and C are viral infections that affect the liver, each spreading in different ways and carrying different risks.
While safe and effective vaccines are available for hepatitis A and B, offering strong, long-lasting protection, there is currently no vaccine for hepatitis C, making screening and early detection especially important.
Together, testing and immunization help protect your liver health and reduce the spread of these preventable and treatable infections.
What's In This Test:
This test detects antibodies that show whether you’ve been exposed to hepatitis. It can identify immunity to hepatitis A and B gained through past infection (natural immunity) or vaccination. It also provides insight into prior hepatitis C exposure or the possibility of a chronic infection, as hepatitis C does not produce immunity.
- Hepatitis A Virus Antibody, IgM and Total test - This blood test detects both IgG and IgM hepatitis A antibodies, but does not differentiate between the two.
- Hepatitis B Virus Surface and Core Antibodies test
- Hepatitis C Virus (HCV) Antibody
Why This Test Matters:
A panel that includes hepatitis A, B, and C antibody testing provides a comprehensive look at your liver health and your potential exposure to the most common viral causes of hepatitis. Each virus spreads differently and affects the body in unique ways, so testing all three at once helps ensure nothing is missed.
- The Hepatitis A antibody test can identify recent or past infection, signalling natural immunity or vaccination history.
- The Hepatitis B surface and core antibody tests also help determine your immunity or exposure history.
- The Hepatitis C antibody test screens for one of the leading causes of chronic liver disease.
Together, these tests give a complete picture of your hepatitis status, helping you and your clinician make informed decisions about follow-up care, immunity, and long-term liver protection.
How Hepatitis Spreads:
Understanding transmission can help you make informed decisions about testing:
- Hepatitis A (HAV) spreads through contaminated food or water, personal contact, or caring for someone who is ill.
- Hepatitis B (HBV) is spread through blood, semen, and vaginal fluids, commonly through sexual contact, household exposure, or shared injection equipment.
- Hepatitis C (HCV) is primarily spread through blood-to-blood contact, often from shared needles or unsterile equipment.
What Your Results May Indicate:
- Negative Result: No signs of hepatitis infection were detected.
- Positive Result: You may have a current or past infection. Additional testing may be performed to confirm active infection, such as a follow-up Hepatitis C RNA test for those with a positive hepatitis C antibody.
Who Is at Higher Risk?
While anyone can be infected, risk increases with certain behaviours or exposures.
Higher Risk for Hepatitis A
- Close contact with someone infected
- Travel to countries where hepatitis A is common
- Men who have sex with men
- Drug use (injection or non-injection)
- Certain clotting disorders
- Occupational exposure to nonhuman primates
CDC Screening Recommendations for Hepatitis B
- People born in regions with high HBV rates
- Men who have sex with men
- People who inject drugs
- People with HIV
- Individuals needing immunosuppressive therapy
- Those with elevated liver enzymes
- People with end-stage renal disease
- Pregnant individuals
CDC Screening Recommendations for Hepatitis C
- Adults born between 1945–1965
- Anyone who has ever injected drugs, even once
- People on long-term hemodialysis
- Individuals with persistent abnormal liver tests
- People with HIV
- Recipients of blood products or organ transplants before 1992
- Healthcare or occupational exposures to HCV-positive blood
Why You Shouldn’t Wait To Test:
When hepatitis goes undiagnosed, the virus can continue damaging the liver without you realising it, often for years. Because many people have few or no symptoms, the infection can quietly progress and lead to serious health complications, including:
- Chronic liver inflammation: Ongoing inflammation gradually weakens the liver and reduces its ability to function properly.
- Liver scarring (cirrhosis): Long-term damage can lead to scar tissue replacing healthy liver tissue. Cirrhosis is irreversible and can cause significant health problems.
- Liver failure: As liver function declines, the body can no longer filter toxins, produce essential proteins, or support digestion, leading to life-threatening complications.
- Liver cancer: Chronic hepatitis B and C significantly increase the risk of developing hepatocellular carcinoma, the most common form of liver cancer.
- Serious health symptoms over time: Untreated hepatitis can eventually cause jaundice, abdominal swelling, confusion, bleeding disorders, and extreme fatigue as the liver deteriorates.
- Transmission to others: Without knowing your status, you may unintentionally put partners or household members at risk.
Delaying testing can leave you unsure about your health and unaware of a potential hepatitis infection that may already be affecting your liver. Because many people experience mild or no symptoms, waiting can allow silent damage to progress without your knowledge. Testing now provides clarity, helps protect your long-term liver health, and ensures you can take the right steps sooner rather than later. Early awareness empowers you to safeguard both yourself and those around you.
Who Should Consider This Test?
- Some schools require proof of immunization for certain vaccines, so if you don’t have your vaccination records, some schools will accept our results for this panel of blood antibody tests (titers) as proof of immunity. These tests show whether you’re already protected from certain diseases and can serve as an alternative when records are missing or incomplete. Requirements vary by state, school district, age group (K–12 vs. college), and program (e.g., healthcare, nursing, childcare programs often require additional proof of immunity)
- If you’re considering vaccinations for hepatitis A and B but can’t remember whether you’ve already been immunized, this test can help confirm your status so you don’t receive unnecessary repeat doses.
- You may also want to get tested if you believe you’ve been exposed to hepatitis, even if you feel completely well.
Testing is always recommended for anyone experiencing symptoms of liver inflammation, including:
- Fever
- Nausea or vomiting
- Loss of appetite
- Dark urine or pale stool
- Jaundice (yellowing of the skin or eyes)
- Abdominal discomfort
- Fatigue
Many people with hepatitis, especially hepatitis C, may have mild or no symptoms at all, sometimes for years. That’s why proactive testing is key.
110% Price Guarantee!
If you find the same test for a lower price from a comparable provider, contact us. We not only match the price, we beat it by an additional 10 percent of the difference.
Common Questions:
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What does it mean to have immunity to hepatitis A and B?
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Why would I need hepatitis immunity testing?
You may need testing if you don’t have vaccination records, are starting a new job or school program that requires proof of immunity, or want to confirm whether you’re protected after vaccination.
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Can I have antibodies from a past hepatitis infection without realizing I ever had it?
Yes. Many hepatitis infections, especially hepatitis A and B, can be mild or unnoticed. Antibody testing can reveal past exposure even if you never experienced symptoms.
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Do I need to fast before this test?
Fasting is not required for this test. You can eat and drink normally unless your doctor has given you other instructions.
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Will anyone see my results besides me?
Your results are stored in your secure online account. They are not shared with anyone else. If you choose, you can print or download them to share with your own doctor.
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Can I talk to someone about my results?
Yes. If your results come back positive or if you simply have questions, our team is here to support you. You can text our Patient Services team at 1800-579-3914, anytime between 8am and 8pm.
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Can I use insurance to pay for this test?
In order to ensure your privacy, we do not bill insurance directly, but you may use HSA or FSA funds. This keeps your results and testing completely private from insurers. We can also provide you with an itemized receipt for insurance reimbursement purposes if you need it.
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What type of sample is required for this test?
This test requires a simple blood draw. No urine samples, swabs, or physical exams are involved.